Kenichiro Ishii Selected Research

naftopidil

1/2018	Additive naftopidil treatment synergizes docetaxel-induced apoptosis in human prostate cancer cells.
6/2017	Combination treatment with naftopidil increases the efficacy of radiotherapy in PC-3 human prostate cancer cells.
1/2015	Identification of a new pharmacological activity of the phenylpiperazine derivative naftopidil: tubulin-binding drug.
9/2013	Oral naftopidil suppresses human renal-cell carcinoma by inducing G(1) cell-cycle arrest in tumor and vascular endothelial cells.
1/2011	Naftopidil, a selective {alpha}1-adrenoceptor antagonist, suppresses human prostate tumor growth by altering interactions between tumor cells and stroma.
1/2008	Naftopidil, a selective alpha-1 adrenoceptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest.

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Kenichiro Ishii Research Topics

Disease

24	Prostatic Neoplasms (Prostate Cancer) 12/2020 - 01/2004
18	Neoplasms (Cancer) 12/2020 - 08/2004
2	Idiopathic Pulmonary Fibrosis 01/2019 - 01/2019
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2019 - 05/2009
2	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 06/2017 - 01/2015
1	Phyllodes Tumor (Cystosarcoma Phylloides) 12/2020
1	Breast Neoplasms (Breast Cancer) 12/2020
1	Granulomatous Mastitis 12/2020
1	Genomic Instability 07/2020
1	Chromosome Breakage 07/2020
1	Drug-Related Side Effects and Adverse Reactions 01/2019
1	Urologic Diseases (Urinary Tract Disease) 01/2019
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2019
1	Urinary Bladder Neoplasms (Bladder Cancer) 10/2018
1	Carcinoma (Carcinomatosis) 04/2018
1	Colonic Neoplasms (Colon Cancer) 01/2015
1	Renal Cell Carcinoma (Grawitz Tumor) 09/2013
1	Starvation 06/2009
1	Residual Neoplasm 05/2009
1	Lymphatic Metastasis 05/2009
1	Lower Urinary Tract Symptoms 01/2008
1	Hyperplasia 01/2008
1	Neoplasm Metastasis (Metastasis) 05/2006
1	Carcinogenesis 06/2005
1	Castration-Resistant Prostatic Neoplasms 01/2004

Drug/Important Bio-Agent (IBA)

16	AndrogensIBA 07/2020 - 01/2004
7	Androgen Receptors (Androgen Receptor)IBA 09/2019 - 01/2004
7	Hormones (Hormone)IBA 12/2011 - 08/2004
6	Prostate-Specific Antigen (Semenogelase)IBA 09/2019 - 04/2004
6	naftopidilIBA 01/2018 - 01/2008
2	Proteins (Proteins, Gene)FDA Link 12/2020 - 03/2016
2	Phenobarbital (Luminal)FDA Link 12/2020 - 07/2014
2	SteroidsIBA 12/2020 - 05/2006
2	Pharmaceutical PreparationsIBA 01/2019 - 01/2018
2	pirfenidoneIBA 01/2019 - 01/2019
2	Capsules (Microcapsules)IBA 09/2013 - 09/2007
2	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2011 - 01/2008
1	Paclitaxel (Taxol)FDA LinkGeneric 12/2020
1	VimentinIBA 12/2020
1	Actin Depolymerizing Factors (Cofilins)IBA 12/2020
1	Tyrosine Kinase InhibitorsIBA 01/2019
1	Imatinib Mesylate (Gleevec)FDA Link 01/2019
1	Indicators and Reagents (Reagents)IBA 01/2019
1	nilotinib FDA Link 01/2019
1	Protein Isoforms (Isoforms)IBA 10/2018
1	MicroRNAs (MicroRNA)IBA 04/2018
1	Biomarkers (Surrogate Marker)IBA 04/2018
1	CytokinesIBA 01/2018
1	Docetaxel (Taxotere)FDA Link 01/2018
1	Interleukin-6 (Interleukin 6)IBA 01/2018
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018
1	phenylpiperazineIBA 01/2015
1	Transforming Growth Factors (Transforming Growth Factor)IBA 10/2014
1	Dinoprostone (PGE2)FDA Link 10/2014
1	silodosin FDA Link 01/2011
1	Tamsulosin (Flomax)FDA LinkGeneric 01/2011
1	Insulin-Like Growth Factor I (IGF-1)IBA 06/2009
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 06/2009
1	Growth Factor ReceptorsIBA 06/2009
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 06/2009
1	Messenger RNA (mRNA)IBA 06/2009
1	AntigensIBA 05/2009
1	CarbohydratesIBA 05/2009
1	DNA (Deoxyribonucleic Acid)IBA 06/2005
1	Peptide Hydrolases (Proteases)FDA Link 04/2004
1	Kallikreins (Kallikrein)IBA 04/2004
1	MetallothioneinIBA 01/2004
1	ZincIBA 01/2004

Therapy/Procedure

10	Therapeutics 12/2020 - 08/2004
5	Castration 09/2019 - 08/2004
2	Operative Surgical Procedures 12/2020 - 02/2013
1	Segmental Mastectomy (Lumpectomy) 12/2020
1	Mastectomy (Mammectomy) 12/2020
1	Radiotherapy 06/2017
1	Drug Therapy (Chemotherapy) 02/2013
1	Oral Administration 01/2008
1	Chemoprevention 01/2008